Predisposing factors for adrenal insufficiency

Author:

Bornstein SR

Date: 11 June 2009

Abstract:

No abstract. First paragraph: Adrenal insufficiency — the clinical manifestation of deficient production or action of glucocorticoids — is a life-threatening disorder that may result from either primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic-pituitary axis. This article focuses on providing the practicing clinician with new insights into predisposing factors for adrenal insufficiency. When and during what situations should a clinician suspect adrenal insufficiency? What genetic disorders, infections, and medications should be considered? What are the current views on the underlying mechanisms?

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