Early diagnosis of invasive fungal infections of caused by Aspergillus and other emerging mycelial fungi / Estado actual del diagnà³stico precoz de las infecciones invasoras causadas por Aspergillus y otros hongos filamentosos emergentes

Author:

del Palacio A, Alhambra A, CuÉtara MS, Pontón J

Date: 16 October 2007

Abstract:

The usefulness of surrogate markers in the diagnosis of invasive fungalinfections caused by Aspergillus and other emerging mycelial fungi is basedon the ability of surrogate markers to detect the infection caused by differentspecies of mycelial fungi. Conventional microbiological methods for diagnosisof fungal disease are slow and insensitive. Antigen based assays ormeasurement of (1-3)-β-D-glucan in blood have been developed and validatedin clinical laboratories. We review these diagnostic contemporary tools, theirclinical application and impact.

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