Author:

Pounder JI, Simmon KE, Barton CA, Hohmann SL, Brandt ME, Petti CA

Date: 21 December 2006

Abstract:

Fungal infections are increasing, particularly among immunocompromised hosts, and a rapid diagnosis is essential to initiate antifungal therapy. Often fungi cannot be identified by conventional methods and classified as nonsporulating molds (NSM).We sequenced internal transcribed spacer (ITS) regions from 50 cultures of NSM and found 16 potential pathogens that can be associated with clinical disease. In select clinical settings, identification of NSM could prove valuable and have immediate impact on patient management.

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