Cross reactions to antigens causing hypersensitivity pneumonitis
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Date: 1 June 1974
Abstract:
The sera of patients with asthma, aspergillosis, pigeon breeder’s disease, farmer’s lung, and a hypersensitivity pneumonitis in textile plant workers were screened by gel diffusion against a variety of fungal antigens and dust extracts. Patients with hypersensitivity pneumonitis were especially prone to develop precipitating antibody to numerous airborne antigens. From the results it was concluded that patients with hypersensitivity pneumonitis form precipitating antibodies to definite groups of antigens in their environment. Most of the patients had precipitins to house dust that formed lines of identity with fungi and thermophilic actinomycetes.
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