Calcineurin localizes to the hyphal septum in Aspergillus fumigatus: implications for septum formation and conidiophore development

Author:

Juvvadi PR, Fortwendel JR, Pinchai N, Perfect BZ, Heitman J, Steinbach WJ

Date: 25 July 2008

Abstract:

A functional calcineurin A fusion to GFP (CnaA-EGFP) was expressed in the Aspergillus fumigatus ΔcnaA mutant. CnaA-EGFP localized in actively growing hyphal tips, at the septa, and at junctions between the vesicle and phialides in an actin-dependent manner. This is the first study to implicate calcineurin in septum formation and conidiophore development of a filamentous fungus.

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