Breakthrough Fungal Infections in Patients With Leukemia Receiving Isavuconazole

Breakthrough Fungal Infections in Patients With Leukemia Receiving Isavuconazole

Author:

Caitlin R RauschAdam J DiPippoPrithviraj BoseDimitrios P Kontoyiannis

Date: 30 October 2018

Abstract:

We retrospectively assessed breakthrough invasive fungal infections (b-IFIs) in 100 consecutive patients with leukemia receiving single-agent isavuconazole; 13 had documented b-IFIs (candidiasis in 6, mucormycosis in 4). All b-IFIs were observed in patients with prolonged neutropenia and active leukemia.

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