Resistance of fungi to the antifungal drugs intended to control their growth is clearly of fundamental importance to the treatment of an infected person.

Consequently there is a lot of research effort put in to identifying and describing the mechanisms of resistance used by the fungi, ranging from cellular membrane pumps that remove the drug from the fungal cell to biofilm mats that offer physical resistqance to the entry of the drug into a mass of hyphae.

We have identified several recent papers that review antifungal drug resistance and list them here, as well as other related papers.

 

  Invasive mycoses: evolving challenges and opportunities in antifungal therapy (multimedia activity) by Perfect JR, Pfaller MA, Ostrosky-Zeichner L, Kontoyiannis DP Link
  Azole Antifungal Resistance Today: Focus on Aspergillus by Bowyer P, Moore CB, Rautemaa R, Denning DW, Richardson MD Link
  Regulatory circuitry governing fungal development, drug resistance, and disease by Shapiro RS, Robbins N, Cowen LE Link
  Epidemiology and Antifungal Resistance in Invasive Aspergillosis according to Primary Disease - Review of the Literature by Mayr A, Lass-Flörl C Link
  Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection by Howard SJ, Arendrup MC Link
  Aspergillus species intrinsically resistant to antifungal agents by Van Der Linden JW, Warris A, Verweij PE Link
  Central nervous system infectious complications early after liver transplantation by Feltracco P, Barbieri S, Furnari M, Milevoj M, Rizzi S, Galligioni H, Salvaterra F, Zanus G, Cillo U, Ori C Link
  Chronic aspergillus infections of the respiratory tract: diagnosis, management and antifungal resistance by Izumikawa K, Takazono T, Kohno S Link
  In vitro susceptibility testing in fungi: a global perspective on a variety of methods by Lass-Flörl C, Perkhofer S, Mayr A Link
  Antifungal drug resistance: do molecular methods provide a way forward? by Perlin DS Link
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