| Central nervous system : Meningitis by David W Denning |
|---|
| Meningitis due to Aspergillus is an uncommon clinical entity with approximately 40 cases reported. In all cases it is defined by culture of Aspergillus from the CSF or biopsy of the meninges. The affected host groups are slightly different from those with most other forms of invasive aspergillosis. A number of cases have resulted from extension of disease from the paranasal sinuses. At least 3 cases have occurred in intravenous drug users and other cases have followed neurosurgery or administration of intrathecal antibiotics. Other underlying disorders include leukaemia, systemic lupus erythematosus, tuberculosis, sarcoidosis and diabetes mellitus. At least 3 cases have occurred in otherwise healthy individuals. more... |