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Whilst the Aspergillus Website & the Fungal Research Trust have taken every precaution in compiling this site, neither it nor any contributors or charity Trustees can be held responsible for using the information held herein. Medical information changes constantly and the information presented here should not be considered complete or exhaustive and should not be relied upon as the sole or primary source on which to base diagnosis or treatment for any individual. This site is not designed to and does not provide medical advice, professional diagnosis, opinion, treatment or services to you or to any other individual. Through this site and links to other sites, the Aspergillus Website provides general information for educational purposes only. The information provided in this site, or through links to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call, consultation or the advice of your physician or other healthcare provider. Neither The Aspergillus Website nor the FRT is liable or responsible for any advice, course of treatment, diagnosis or any other information, services or product you obtain through this site. I have read this, proceed to the article |
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Oral aspergillosis |
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Until recently most cases of oral aspergillosis were thought to represent spread from the nose or sinuses (Schubert 1986, Chambers 1995) . Infection starting at the gingival margin ( manifest as painful necrosis) and spreading rapidly to the contiguous mucosa, muscle and bone in neutropenic patients has now been described (Sugata, 1994). In addition aspergillosis of the tongue has been described in AIDS at autopsy (Leonard 1997). Control of disease is possible with systemic antifungal therapy, local debridement of affected tissues and recovery of neutropenia. In cases where there is spread from the sinuses or nose surgical therapy is necessary for diagnosis. The impact of major surgical resection is probably small (Denning 1990, Kennedy 1997) and should be reserved for cases with no other therapeutic avenue. David W. Denning FRCP FRCPath FIDSA FMedSci April 1998
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