Aspergillus Genomics
Neosartorya fischeri / Aspergillus fischerianus

1. Genome project overview

   An overview of the genome project can be found at the NCBI website.

2. Unannotated genome sequence

   The unannotated genome sequence of the type strain NRRL 181 of Neosartorya fischeri, a teleomorph of Aspergillus fischerianus, has been publicly released by The Institute for Genomic Research (TIGR). The 11.0 x assembly consists of 1380 contigs that cover 33.2 Mb; the contigs have been linked to form 1174 scaffolds. The assembly is available for BLAST searching at NCBI by selection of the non-redundant (nr) or whole genome shotgun (wgs) databases.

   This project was funded by the National Institute of Allergy and Infectious Disease as part of a larger Aspergillus comparative genomics effort involving the Microbial Sequencing Centers at the Broad Institute and at TIGR. The larger project was created through a white paper submitted by Bruce Birren (Broad), Bill Nierman (TIGR) and David Denning (The University of Manchester).

3. Comparative analysis of an emerging fungal pathogen, Aspergillus terreus

   The document puts forward a case for the sequencing of the genome of Neosartorya fischeri / Aspergillus fischerianus for use in comparative analysis of the genomes of significant pathogens in the Aspergilli, such as A.terreus and A.fumigatus.