Aspergillus Genomics - Aspergillus clavatus

1. Genome project overview

   An overview of the genome project can be found at the NCBI website.

2. Unannotated genome sequence

   The unannotated genome sequence of the type strain NRRL 1 of Aspergillus clavatus has been publicly released by The Institute for Genomic Research (TIGR). The 11.4 x assembly of Aspergillus clavatus consists of 322 contigs that cover 27.9 Mb; the contigs have been linked to form 240 scaffolds. The assembly is available for BLAST searching at NCBI by selection of the non-redundant (nr) or whole genome shotgun (wgs) databases.

   This project was funded by the National Institute of Allergy and Infectious Disease as part of a larger Aspergillus comparative genomics effort involving the Microbial Sequencing Centers at the Broad Institute and at TIGR. The larger project was created through a white paper submitted by Bruce Birren (Broad), Bill Nierman (TIGR) and David Denning (The University of Manchester).

3. Comparative analysis of an emerging fungal pathogen, Aspergillus terreus

   The document puts forward a case for the sequencing of the genome of Aspergillus clavatus for use in comparative analysis of the genomes of significant pathogens in the Aspergilli, such as A.terreus and A.fumigatus.