Dear Dr Denning and JEEN,
Did you find any references to the CF delta f508 gene?
I am interested to see if there are any evidence of ABPA being hereditary
thanks
David Adamson
> Dr Denning;
>
> I have written you before. I have had confirmed ABPA for 23 years. I have been on steriods, high doses for most of my life. When I get an exercerbation I take sporonox, antibiotics, etc. Recently mycobacteriun Kansaii was cultured from a bronchoscopy I had, and I went to a hospital in Denver CO, National Jewish, which specializes in lung diseases to see if they could get a handle on why I was becoming more ill more frequently.
>
> They found I was a carrier of the CF gene Delta F 508. I have since found two studies that link this one gene to ABPA and severe asthma. Do you know of this and are there more studies you can alert me to. I am now taking pulmozyme and using the flutter as well.
>
> Thank you
>
> Jeen