Secondary metabolites trivial name - sphingofungin B
Species A. fumigatus
Systematic name 6-Eicosenoic acid, 2-amino-3,4,5,14-tetrahydroxy- (2S,5S,3R,4R,14R)-2-Amino-3,4,5,14-tetrahydroxyicos-6-enoic acid
Molecular formulae C20H39NO6
Molecular weight 389.527
Chemical abstracts number 121025-45-4
PubChem URL Go to PubChem link
Selected references VanMiddlesworth F, Giacobbe RA, Lopez M, Garrity G, Bland JA, Bartizal K, Fromtling RA, Polishook J, Zweerink M, Edison AM, et al. J Antibiot (Tokyo). 1992 Jun;45(6):861-7. Sphingofungins A, B, C, and D; a new family of antifungal agents. I. Fermentation, isolation, and biological activity.
Zweerink MM, Edison AM, Wells GB, Pinto W, Lester RL. Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase. J Biol Chem. 1992 Dec 15;267(35):25032-8.
Structure diagram
3D Structure
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