Secondary metabolites trivial name - citreoviridin
Species A. terreus
Systematic name D-Iditol, 2,5-anhydro-1,6-dideoxy-2-C-[(1E,3E,5E,7E)-8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1,3,5,7-octatetraenyl]-4-C-methyl- (9CI)
Molecular formulae C23H30O6
Molecular weight 402.481
Chemical abstracts number 25425-12-1
PubChem URL Go to PubChem link
Selected references Franck B, Gehrken HP. Angew Chem Int Ed Engl. 1980;19(6):461-2 Citreoviridins from Aspergillus terreus.
Toxicity Citreoviridin is produced by P. citreonigrum (synonyms P. citreoviride and P. toxicarium), particularly in rice after harvest. It can cause cardiac beriberi in man. Acute cardiac beriberi in Japan is now only of historical interest although P. citreonigrum and citreoviridin are still reported in other parts of Asia. The fungus is said to be favoured by the lower temperatures and shorter hours of daylight occurring in the more temperate rice growing areas. The toxin is also produced by P. ochrosalmoneum. Citreoviridin has been found in un-harvested corn in the USA. Citreoviridin is an unusual molecule consisting of a lactone ring conjugated to a furan ring, with a molecular weight of 402. It is a neurotoxin. Nishie K, Cole RJ, Dorner JW. Res Commun Chem Pathol Pharmacol. 1988 Jan;59(1):31-52.Toxicity of citreoviridin.
Structure diagram
3D Structure
Automatic database searches PubMed - 15 million citations from MEDLINE and other life science journals.
Search Pubmed for citreoviridin
ChemIDplus - Dictionary of over 370,000 chemicals (names, synonyms, and structures).
Search by chemical abstracts number: 25425-12-1
ChemIDplus - Dictionary of over 370,000 chemicals (names, synonyms, and structures). Search by trivial name: citreoviridin
Search Toxicology Literature Online (TOXLINE) Search TOXLINE for citreoviridin
Search Developmental and Reproductive Toxicology Database (DART) Search DART for citreoviridin
Genetic Toxicology Data Bank (GENE-TOX) Search GENE-TOX for citreoviridin
   
back

Disclaimer | Privacy/Confidentiality | Cookies | Terms and Conditions | Advertising
This page was created by Dr Graham Atherton PhD on March 13 2006
This page was last modified: February 06 2013 11:52:22.
Maintained by Aspergillus Website Team