Secondary metabolites trivial name - Cytochalasin E
Species A. clavatus
Systematic name 14-Benzyl-6-hydroxy-4,6,15,15a-tetramethyl-3,13,14,14a,15,15a,16a,16b-octahydro[1,3]dioxacyclotridecino[4,5-d]oxireno[2,3-f]isoindole-5,10,12(4H,6H)-trione
Molecular formulae C28H33NO7
Molecular weight 495.57
Chemical abstracts number 36011-19-5
PubChem URL Go to PubChem link
Toxicity The cytochalasins inhibit cleavage in cultured animal cells leading to the formation of multinucleated cells and cells without nuclei. Cytochalasin E is one of the most acutely toxic of the group causing necrosis of many body organs and pulmonary haemorrhage. Oral LD50 in rats 9.1 mg/kg body-weight.
Structure diagram
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