Secondary metabolites trivial name - 9-deacetoxyfumigaclavine C
Species A. fumigatus (Sartorya fumigata)
Systematic name Not Known
Molecular formulae C21H28N2
Molecular weight 309.2325
Chemical abstracts number Not known
PubChem URL Go to PubChem link
Selected references J. Nat. Prod., Article ASAP DOI: 10.1021/np800700e Publication Date (Web): 03 March 2009
Toxicity Cytotoxicity against KB (human nasopharynyeal epidermoid), MCF-7 (human breast adenocarcinoma), and K562 (human leukemia) cancer cell lines. It showed inhibition with an apparent selectivity for K562 cells, with IC50 values of 41.0 ( 4.6 ). It is noteworthy that the activity of metabolite 2 is close to that of doxorubicin hydrochloride (1.2 ( 0.2 μM), a presently prescribed drug for the treatment of leukemia.
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