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Aspergillosis Patient Support

Formerly Aspergillus Trust and
Aspergillus Website for Patients

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Aspergillus for Patients Meeting, Rome, Feb 3rd, 2010
The following talk from this international meeting was recorded especially for patients with aspergillus related problems- designed to provide a resource for patients and address some of their questions.

How Important is Aspergillus in Cystic fibrosis?

By Richard Moss

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How important is Aspergillus in cystic fibrosis?
Richard B Moss MD
Department of Pediatrics, Stanford University, California, USA

Cystic fibrosis (CF) occurs in 1 in 4,000 births, and there are approximately 70,000 people worldwide who have CF. Aspergillus lung infection is often found in people with CF, is more common in adults and becomes increasingly common as lung function declines.

CF often has some of the features of allergic bronchopulmonary aspergillosis (ABPA), and ABPA may be diagnosed in people with CF when there is evidence of clinical deterioration, a high IgE level, an allergic reaction to

Aspergillus on skin or blood testing, presence of IgG antibodies and new abnormalities on chest X-ray.

As ABPA hastens the loss of lung function in CF, there is an argument for screening for ABPA in people with CF from school age, and treating the condition with corticosteroids and antifungals.

With thanks to Fran Stokes

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