Invasive Pulmonary Aspergillosis in leukaemia,
pt TH
Bilateral diffuse
invasive pulmonary aspergillosis, proven by transbronchial biopsy after resolution
of neutropenia. He was treated with oral itraconazole 400mg daily with a good
outcome. His case was reported in Denning DW, Lee JY, Hostetler JS, Pappas P,
Kauffman CA, Dewsnup DH, Galgiani JN, Graybill JR, Sugar AM, Catanzaro A, Gallis
H, Perfect JR, Dockery B, Dismukes WE, Stevens DA, NIAID Mycoses Study Group multicenter
trial of oral itraconazole therapy of invasive aspergillosis. Am J Med 1994; 97:
135-144.
A
B
X ray 5/2/90 Before itraconazole
therapy.
X ray 25/4/90 After itraconazole
treatment.
Major improvement, defined as a complete response, after 10 weeks therapy with
itraconazole.