Editorial board

JOHN RICHARD GRAYBILL, M.D graduated from Cornell University Medical School in 1966 and trained in Infectious Diseases and Internal Medicine at Vanderbilt and Johns Hopkins University Hospitals. He moved from Vanderbilt to The Audie Murphy VA Memorial Hospital in 1974 where he is now Professor of Medicine and Chief of Infectious Diseases.

He has published over 175 original papers mostly concerning fungal infections, antifungal therapy and the interface between the immune system and fungi. He has also published a variety of other papers on other infectious disease matters. In addition, he has written over 100 reviews and book chapters on fungal infection and antifungal chemotherapy.

His research interests are wide and particularly include fungal infections prevalent in Central and South America such as paracoccidioidomycosis, sporotrichosis, histoplasmosis and coccidioidomysis. He has been involved in the clinical evaluation of all new antifungal drugs. He has also been instrumental in recruiting patients into protocols developed by the NIAID Mycoses Study Group. He works as part of a team in San Antonio which includes the Fungus Testing Laboratory.

Key contributions to the recent literature include:

• Graybill J.R. Systemic Mycoses in the 21st Century. Infectious Disease Clinics of North America 1995 9(2): 297-311
• Graybill J.R., Bocanegra R., Najvar L.K., Loebenberg D., Luther M.F. Granulocyte colony-stimulating factor and azole antifungal therapy in murine aspergillosis: role of immune suppression. Antimicrobial Agents and Chemotherapy 1998 42:2467-2473
• Graybill J.R., Bocanegra R.,Najvar L., Luther M.F., Loebenberg D. SCH56592 treatment of murine invasive aspergillosis. Journal of Antimicrobial Chemotherapy 1998 42:539-542
• Graybill J.R., Revankar S.G., Patterson T.F. Antifungal Agents and Antifungal Susceptibility Testing. Chapter 9 in Topley & Wilson's Microbiology and Microbial Infections Ninth Edition, Volume 4: Medical Mycology. Eds Ajello, L, Hay, RD, Arnold, London, 1998,  pp163-175.
• Graybill J.R. Itraconazole: managing mycotic complications in immunocompromised patients. Seminar in Oncology 1998 25 (Suppl7): 58-63
• Saag M.S., Cloud G.A., Graybill J.R., Sobel J.D., Tuazon C.U., Johnson P.C., Fessel W.J., Moskovitz B.L., Wiesinger B., Cosmatos D., Riser L., Thomas C., Hafner R., Dismukes W.E. and the National Institute of Allergy and Infectious Diseases Mycoses Study Group. A comparison of itraconazole versus fluconazole as maintenance therapy for AIDS-associated cryptococal meningitis. Clinical Infectious Diseases 1999 28:291-296
• Graybill J.R. The role of murine models in the development of antifungal therapy for systemic mycoses. Drug Resistance Updates 2000 Dec;3(6):364-383.
• Graybill J.R. Hitting a new target with echinocandins. Why chase something else? Current Opinion in Investigational Drugs 2001 Apr;2(4):468-71.
• Loeffler J., Kloepfer K., Hebart H., Najvar L., Graybill J.R., Kirkpatrick W.R., Patterson T.F., Dietz K., Bialek R., Einsele H. Polymerase chain reaction detection of aspergillus DNA in experimental models of invasive aspergillosis. Journal of Infectious Diseases. 2002 Apr 15;185(8):1203-6
• Graybill J.R., Bocanegra R., Gonzalez G.M., Najvar L.K. Combination antifungal therapy of murine aspergillosis: liposomal amphotericin B and micafungin. Journal of Antimicrobial Chemotherapy 2003 Oct;52(4):656-62.
• Najvar L.K., Cacciapuoti A., Hernandez S., Halpern J., Bocanegra R., Gurnani M., Menzel F., Loebenberg D., Graybill J.R. Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories. Antimicrobial Agents and Chemotherapy 2004 Mar;48(3):758-64.
• Graybill JR, Hernandez S, Bocanegra R, Najvar LK. Antifungal therapy of murine Aspergillus terreus infection. Antimicrob Agents Chemother. 2004 Oct;48(10):3715-9.
• Harrison JM, Glickman RD, Ballentine CS, Trigo Y, Pena MA, Kurian P, Najvar LK, Kumar N, Patel AH, Sponsel WE, Graybill JR, Lloyd WC 3rd, Miller MM, Paris G, Trujillo F, Miller A, Melendez R. Retinal function assessed by ERG before and after induction of ocular aspergillosis and treatment by the anti-fungal, micafungin, in rabbits. Doc Ophthalmol. 2005 Jan;110(1):37-55.

Contact: E-mail: JRGraybill@aol.com