Clinical & Information Architect
Graham Atherton BSc
MSc (IT) PhD MBCS
1980-83 BSc (Genetics) at Liverpool University followed by
a short period as Lecturer in Genetics at the University of Ulster (1983-84).
Postgraduate at the University of the West of England (1984-87)
where I did a PhD with Professor Alan Vivian working on the molecular genetics
of the specificity of the host-parasite interaction between Pea blight (Pseudomonas
syringae pv. Pisi) and its natural host Pisum sativum.
Postdoctoral position with Professor John Wyke at the Beatson
Institute for Cancer Research (1987-91) working on putative transcriptional
silencing elements present in the rat genome.
Higher Scientific Officer with John Norton at the Paterson
Institute for Cancer Research (1991-00) working on the biological characterisation
of a small helix-loop-helix protein (Id3) cloned from human B cells.
I have worked on the Aspergillus website and related projects since March 2000, managing it since 2001. I have extensively retrained in IT, culminating in the award of an MSc in Information Technology at the University of Liverpool in July 2005.
I set up and ran the Clinical Trials Database System at the University of Manchester (running since July 2003, completed in 2008), which was used to carry out several trials across europe. The results of one of these studies (the FAST study) has since been published - see below.
The National Aspergillosis Centre was opened in April 2009 and I have been leading the Quality of Life assessment and research program as well as the online patient support systems at the centre since its inception.
Representative publications
- Denning DW, O'Driscoll BR, Powell G, Chew F, Atherton GT, Vyas A, Miles J, Morris J, Niven RM. Am J Respir Crit Care Med. 2009 JAN 1;179(1):11-8.Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study. abstract
- Mabey Gilsenan JE, Atherton G, Bartholomew J, Giles PF, Attwood TK, Denning DW, Bowyer P. Nucleic Acids Res. 2009 JAN;37(Database issue):D509-14. Aspergillus genomes and the Aspergillus cloud. abstract
- Yates PR, Atherton GT, Deed RW, et.al. EMBO J
18: (4) 968-976 FEB 15 1999. Id helix-loop-helix proteins inhibit nucleoprotein
complex formation by the TCF ETS-domain transcription factors. abstract
- Norton JD, Atherton GT. Mol Cell Biol 18: (4) 2371-2381
APR 1998. Coupling of cell growth control and apoptosis functions of Id proteins. abstract
- Deed RW, Hara E, Atherton GT, et. al. Mol Cell
Biol 17: (12) 6815-6821 DEC 1997. Regulation of Id3 cell cycle function
by Cdk-2-dependent phosphorylation. abstract
- Vivian A, Atherton GT, Bevan JR, et. al. Physiol
Mol Plant Pathol 34: (4) 335-344 APR 1989. Isolation and characterisation
of cloned DNA conferring specific avirulence in Pseudomonas-syringae p.v.
pisi to Pea (Pisum sativum) cultivars, which possess the resistance allele,
R2. full text
- Bavage AD, Vivian A, Atherton GT, et. al. J Gen
Microbiol 137: 2231-2239 Part 9 SEP 1991. Molecular-genetics of pseudomonas-syringae
pathovar pisi - plasmid involvement in cultivar-specific incompatibility.
abstract
E-mail: gatherton@manchester.ac.uk