Swollen hyphae germinate in the lung and induce NET formation.

A wild type mouse was treated as described for Video S4. The movie shows a series of Z-slices through a large fungal mass with clearly detectable outgrowing hyphae as well as NET-structures at the periphery of the mass and the borders of alveoli. Afterwards, the whole Z-stack is 3-D rendered and rotated to demonstrate the 3-D appearance of the fungal ball relative to the lung structures. Dimensions of the stack are given at the bottom.
Reference: Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA. Bruns et. al. PLoS Pathog. 2010 Apr 29;6(4):e1000873.
http://www.plospathogens.org/article/...

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