“Molecular and Cellular Basis of Antifungal Immunity”
The Hohl laboratory is located at Memorial Sloan Kettering Cancer Center (MSKCC) and is housed within the Immunology Program in the Zuckerman Research Building. MSKCC offers a rich scientific environment and proximity to Weill Cornell Medical College and Rockefeller University.
We study the interactions between human fungal pathogens and mammalian host organisms, with emphasis on the filamentous mold, Aspergillus fumigatus. We develop innovative fluorescence-based methods to visualize fungal cell - host cell encounters with single event resolution and to decipher the events associated with fungal escape or host control of infectious challenges. Recent work focuses on the mechanisms of fungal recognition, innate immune activation, and on host induction of programmed cell death in fungi as a form of mucosal immune surveillance.
Relevant publications from the lab include:
• Jhingran et al., Cell Reports 2:1762-1773, 2012.
• Ngo et al., Journal of Infectious Diseases. 209:109-119, 2014.
• Jhingran et al., PloS Pathogens. 11:e1004589, 2015.
• Kasahara et al., Journal of Infectious Diseases. 213:1289-1298, 2016.
• Shlezinger et al., Science (in press; scheduled for publication on September 8, 2017)
We are seeking a highly motivated individual with an M.D. or Ph.D. degree in microbiology and/or immunology or related fields. The candidate is expected to apply for funding opportunities and should have significant prior research experience and a solid publication record. He or she will possess excellent verbal and written communication skills. Recent graduates with less than 2 years of post-doctoral training and experience in fungal pathogenesis, innate and/or adaptive immunity, and animal or tissue culture models of infection are preferred.
Candidates should send a cover letter containing a statement of interest, future goals, curriculum vitae, and names of three references from mentors familiar with their scientific abilities to [email protected].
Please include "Postdoc Application" in the email subject line.